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Mathematics of Sequence Evolution: Biological Models and ApplicationsMonth: September 2013 Date: September 23--27 Name: Mathematics of Sequence Evolution: Biological Models and Applications Location: Centre de Recherches Mathématiques, Montréal, Canada. DescriptionModels of evolution of biological sequences have gone a long way since Jukes and Cantor. First, it is no longer acceptable to consider that mutations of a given type occur independently and uniformIy across time and space. A large number of factors affect the rate at which mutations occur. Second, selective pressure makes that the probability of fixation of a mutation depends on the fitness of the mutated individual, which sometimes places unexpected constraints on the mutational process and induces strong dependencies between positions along the sequences. SupportFinancial support is available. Information |
