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MBI Workshop 2: Metastasis and Angiogenesis

Month: October 2014

Date: October 13--17

Name: MBI Workshop 2: Metastasis and Angiogenesis

Location: Mathematical Biosciences Institute, The Ohio State University, Jennings Hall 3rd Floor, 1735 Neil Ave., Columbus, Ohio.


This workshop will address the mathematical and computational issues that arise from models of angiogenesis and metastasis. Such models are frequently hybrid models, that describe cells (either those building the vessel or those involved in metastasis) at a detailed level that treats their biochemical and mechanical responses to their environment, and couple this cell-based description with partial differential equations that describe the mechanics of the surrounding tissue and the reaction and transport of growth factors and chemotactic signals. Major topics to be treated are how to model the movement of single cells through the extracellular matrix, how to describe in sufficient detail the process by which new vessels grow toward a tumor, how to cope with the computational problems raised by such hybrid models, and what the implications are for our understanding of the underlying basic science and how that understanding can be translated into improved therapeutic regimens.

Information; phone: 614-292-3648.