DIMACS: Series in Discrete Mathematics and Theoretical Computer Science 1992; 150 pp; hardcover Volume: 8 ISBN10: 082186601X ISBN13: 9780821866016 List Price: US$59 Member Price: US$47.20 Order Code: DIMACS/8
 This collection contains papers by participants in the seminar on mathematical methods in molecular biology who worked for several years at the Laboratory of Molecular Biology and Bioorganic Chemistry (now the Institute of Physical and Chemical Problems in Biology) at Moscow State University. The seminar united mathematicians and biologists around the problems of biological sequences. The collection includes original results as well as expository material and spans a range of perspectives, from purely mathematical problems to algorithms and their computer realizations. For this reason, the book is of interest to mathematicians, statisticians, biologists, and computational scientists who work with biopolymer sequences. Copublished with the Center for Discrete Mathematics and Theoretical Computer Science beginning with Volume 8. Volumes 17 were copublished with the Association for Computer Machinery (ACM). Readership Mathematicians, statisticians, biologists and computational scientists who work with biopolymer sequences. Table of Contents  I. Some problems of mathematical statistics
 A. M. Leontovich  On the optimality of the Dayhoff matrix for computing the similarity score between fragments of biological sequences
 V. I. Piterbarg  On the distribution of the maximum similarity score for fragments of two random sequences
 II. Surveys and methodology
 M. S. Gelfand  Computer functional analysis of nucleotide sequences: Problems and approaches
 E. V. Koonin  Comparative analysis of biopolymer sequences: Reflections on the validity of the methodology and the underlying general principles
 III. Methods and algorithms
 D. R. Davydov, I. Erlikh, E. E. Klotz, and V. G. Fridman  A new method for recognition of structural and functional motifs in protein sequences based on the principal component analysis of profiles of physicochemical properties
 M. S. Gelfand  Prediction of proteincoding regions in DNA of higher Eukaryotes
 P. Pevzner  DNA physical mapping, flows in networks and minimum cycles mean in graphs
 M. A. Roytberg  Fast algorithm for optimal aligning of symbol sequences
 IV. Software
 L. I. Brodsky, A. V. Vassilyev, Ya. L. Kalaydzidis, Yu. S. Osipov, R. L. Tatuzov, and S. I. Feranchuk  GeneBee: The program package for biopolymer structure analysis
 R. L. Tatuzov and T. A. Mamikonova  Data compression and the use of vector operations for the fast search problems in analysis of biological sequences
 R. L. Tatuzov and T. A. Mamikonova  Organization and storage of information in molecular genetics data banks
